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Paradoxic Decrease in Ischemic Mitral Regurgitation With Papillary Muscle Dysfunction
Author(s) -
Emmanuel Messas,
Jorge Guerrero,
Mark D. Handschumacher,
Chi-Ming Chow,
Suzanne Sullivan,
Ehud Schwammenthal,
Robert A. Levine
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc4101.097112
Subject(s) - medicine , cardiology , papillary muscle , mitral regurgitation , functional mitral regurgitation , mitral valve , regurgitation (circulation) , heart failure , ejection fraction
Ischemic mitral regurgitation (MR) was first ascribed to papillary muscle (PM) contractile dysfunction. Current theories include apical leaflet tethering caused by left ventricular (LV) distortion, but PM dysfunction is still postulated and commonly diagnosed. PM contraction, however, parallels apical tethering, suggesting the hypothesis that PM contractile dysfunction can actually diminish MR due to ischemic distortion of the inferior base alone.

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