Open AccessAngiotensin II Type 1 Receptor Blockade Prevents Lethal Malignant Hypertension
Author(s) -
Karl F. Hilgers,
Andrea Hartner,
Markus Porst,
Roland Veelken,
Johannes F.E. Mann
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc3601.095576
Subject(s) - valsartan , medicine , blood pressure , angiotensin ii , endocrinology , kidney , angiotensin ii receptor type 1 , renin–angiotensin system , renovascular hypertension , pharmacology
Angiotensin II is elevated in malignant hypertension. We tested the hypothesis that angiotensin II type 1 receptor blockade can prevent the development of malignant hypertension even in the absence of a blood pressure-lowering effect.
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