Significance of Chymase-Dependent Angiotensin II–Forming Pathway in the Development of Vascular Proliferation | Zendy

Masayoshi Nishimoto | Zendy; Shinji Takai | Zendy; Shokei Kim | Zendy; Denan Jin | Zendy; Atsushi Yuda | Zendy; Masato Sakaguchi | Zendy; Mayumi Yamada | Zendy; Yoshihide Sawada | Zendy; Keiichiro Kondo | Zendy; Kunio Asada | Zendy; Hiroshi Iwao | Zendy; Shinjiro Sasaki | Zendy; Mizuo Miyazaki | Zendy

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Significance of Chymase-Dependent Angiotensin II–Forming Pathway in the Development of Vascular Proliferation

Author(s) -

Masayoshi Nishimoto,

Shinji Takai,

Shokei Kim,

Denan Jin,

Atsushi Yuda,

Masato Sakaguchi,

Mayumi Yamada,

Yoshihide Sawada,

Keiichiro Kondo,

Kunio Asada,

Hiroshi Iwao,

Shinjiro Sasaki,

Mizuo Miyazaki

Publication year - 2001

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/hc3601.094304

Subject(s) - chymase , medicine , angiotensin ii , renin–angiotensin system , angiotensin ii receptor type 1 , microbiology and biotechnology , endocrinology , immunology , receptor , blood pressure , mast cell , biology

Vascular tissues of humans and dogs contain chymase as an angiotensin II-forming enzyme. In this study, we investigated whether chymase-dependent angiotensin II formation plays a crucial role in the development of vascular proliferation in dog grafted veins.

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