Open AccessLeft Ventricular Remodeling in Transgenic Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor
Author(s) -
Natarajan Sivasubramanian,
Mytsi L. Coker,
Karla Kurrelmeyer,
W. Robb MacLellan,
Francesco J. DeMayo,
Francis G. Spinale,
Douglas L. Mann
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc3401.093154
Subject(s) - matrix metalloproteinase , medicine , tumor necrosis factor alpha , genetically modified mouse , endocrinology , fibrosis , ventricular remodeling , myocardial fibrosis , transgene , necrosis , transforming growth factor , heart failure , biology , biochemistry , gene
The mechanisms responsible for tumor necrosis factor (TNF)-induced LV structural remodeling in the adult heart are not known.
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