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Differential Effects of Angiotensin II Versus Endothelin-1 Inhibitions in Hypertrophic Left Ventricular Myocardium During Transition to Heart Failure
Author(s) -
Yoshitaka Iwanaga,
Yasuki Kihara,
Koichi Inagaki,
Yoko Onozawa,
Takeshi Yoneda,
Kazuaki Kataoka,
Shigetake Sasayama
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc3101.092201
Subject(s) - medicine , heart failure , cardiology , bosentan , angiotensin ii , endothelin receptor , muscle hypertrophy , endothelin 1 , endocrinology , ace inhibitor , left ventricular hypertrophy , angiotensin ii receptor type 1 , losartan , blood pressure , angiotensin converting enzyme , receptor
In view of their mutual crosstalk, the roles of angiotensin II (Ang II) and endothelin-1 (ET-1) in the myocardium are assumed to be synergistic and supplemental.

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