Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice | Zendy

Peter Kuhlencordt | Zendy; Robert Gyurko | Zendy; Fred Han | Zendy; Marielle ScherrerCrosbie | Zendy; Thomas H. Aretz | Zendy; Roger J. Hajjar | Zendy; Michael H. Picard | Zendy; Paul L. Huang | Zendy

Open Access

Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice

Author(s) -

Peter Kuhlencordt,

Robert Gyurko,

Fred Han,

Marielle ScherrerCrosbie,

Thomas H. Aretz,

Roger J. Hajjar,

Michael H. Picard,

Paul L. Huang

Publication year - 2001

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/hc2901.091399

Subject(s) - enos , medicine , apolipoprotein e , cardiology , arteriosclerosis , myocardial infarction , lesion , endocrinology , nitric oxide synthase , pathology , nitric oxide , disease

To test whether deficiency in endothelial nitric oxide synthase (eNOS) affects atherosclerosis development, we compared lesion formation in apolipoprotein E (apoE)/eNOS-double knockout (DKO) and apoE-knockout (KO) control animals.

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