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Phenotype of Infiltrating T Lymphocytes in Cardiac Sarcoidosis
Author(s) -
Michael Schoppet,
Sabine Pankuweit,
Roland Moll,
Ulrik Baandrup,
Bernhard Maisch
Publication year - 2002
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc1202.104524
Subject(s) - university hospital , medicine , sarcoidosis
Apreviously well 29-year-old woman was referred to our hospital after a syncopal attack accompanied by severe congestive heart failure. The ECG showed complete atrioventricular conduction block, which necessitated immediate pacemaker implantation. Echocardiography revealed septal, apical, and lateral hypokinesia with a left ventricular ejection fraction of 23% and a systolic anterior and posterior pericardial effusion of 3 mm. The results of the chest radiograph were normal. Coronary angiography detected no stenotic lesions. The hematoxylin- and eosin-stained sections of a left ventricular endomyocardial biopsy showed noncaseating granulomas with giant cells at onset of disease and …

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