Induction of Functional Bradykinin B 1 -Receptors in Normotensive Rats and Mice Under Chronic Angiotensin-Converting Enzyme Inhibitor Treatment | Zendy

Maria E. MarinCastaño | Zendy; Joost P. Schanstra | Zendy; Eric Neau | Zendy; Françoise Praddaude | Zendy; Christiane Pécher | Zendy; JeanLouis Ader | Zendy; Jean-Pierre Girolami | Zendy; JeanLoup Bascands | Zendy

Open Access

Induction of Functional Bradykinin B ₁ -Receptors in Normotensive Rats and Mice Under Chronic Angiotensin-Converting Enzyme Inhibitor Treatment

Author(s) -

Maria E. MarinCastaño,

Joost P. Schanstra,

Eric Neau,

Françoise Praddaude,

Christiane Pécher,

JeanLouis Ader,

Jean-Pierre Girolami,

JeanLoup Bascands

Publication year - 2002

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/hc0502.102965

Subject(s) - kinin , receptor , receptor antagonist , ace inhibitor , angiotensin converting enzyme , bradykinin receptor , pharmacology , bradykinin , endocrinology , receptor expression , medicine , angiotensin receptor , antagonist , angiotensin ii , blood pressure

The physiological effects of ACE inhibitors may act in part through a kinin-dependent mechanism. We investigated the effect of chronic ACE-inhibitor treatment on functional kinin B(1)- and B(2)-receptor expression, which are the molecular entities responsible for the biological effects of kinins.

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