Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis
Author(s) -
Milton Packer
Publication year - 2022
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.122.061732
Subject(s) - autophagy , sirtuin , ampk , medicine , mitochondrial biogenesis , microbiology and biotechnology , sirtuin 1 , sirt3 , pi3k/akt/mtor pathway , protein kinase a , endocrinology , downregulation and upregulation , pharmacology , signal transduction , biology , mitochondrion , biochemistry , kinase , nad+ kinase , apoptosis , gene , enzyme
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