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Efficacy and Safety of Appropriate Shocks and Antitachycardia Pacing in Transvenous and Subcutaneous Implantable Defibrillators: Analysis of All Appropriate Therapy in the PRAETORIAN Trial
Author(s) -
Reinoud E. Knops,
Willeke van der Stuijt,
Peter Paul H.M. Delnoy,
Lucas V.A. Boersma,
Juergen Kuschyk,
Mikhael F. ElChami,
Hendrik Bonnemeier,
Elijah R. Behr,
Tom F. Brouwer,
Stefan Kääb,
Suneet Mittal,
AnneFloor B.E. Quast,
Lonneke Smeding,
Jan G.P. Tijssen,
Nick R. Bijsterveld,
Sergio Richter,
Marc A. Brouwer,
Joris R. de Groot,
Kirsten M. Kooiman,
Pier D. Lambiase,
Petr Neužil,
Kevin Vernooy,
Marco Alings,
Timothy R. Betts,
Frank Bracke,
Martin C. Burke,
Jonas S.S.G. de Jong,
David J. Wright,
Ward P.J. Jansen,
Zachary I. Whinnet,
Peter Nordbeck,
Michael Knaut,
Berit T. Philbert,
Jurren M. van Opstal,
Alexandru B. Chicos,
Cornelis P. Allaart,
Alida E. Borger van der Burg,
Jude Clancy,
José Dizon,
Marc A. Miller,
Dmitry Nemirovsky,
Ralf Surber,
Gaurav A. Upadhyay,
Raul Weiss,
Anouk de Weger,
Arthur A.M. Wilde,
Louise R.A. Olde Nordkamp,
Jim W. Cheung,
Tjeerd Germans,
Francisco Leyva,
Dominic A.M.J. Theuns
Publication year - 2021
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.121.057816
Subject(s) - medicine , implantable cardioverter defibrillator , ventricular tachycardia , randomized controlled trial , ventricular fibrillation , tachycardia , cardiology , population , defibrillation , shock (circulatory) , environmental health
The PRAETORIAN trial (A Prospective, Randomized Comparison of Subcutaneous and Transvenous Implantable Cardioverter Defibrillator Therapy) showed noninferiority of subcutaneous implantable cardioverter defibrillator (S-ICD) compared with transvenous implantable cardioverter defibrillator (TV-ICD) with regard to inappropriate shocks and complications. In contrast to TV-ICD, S-ICD cannot provide antitachycardia pacing for monomorphic ventricular tachycardia. This prespecified secondary analysis evaluates appropriate therapy and whether antitachycardia pacing reduces the number of appropriate shocks.

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