Hemoglobin and Clinical Outcomes in the Vericiguat Global Study in Patients With Heart Failure and Reduced Ejection Fraction (VICTORIA)
Author(s) -
Justin A. Ezekowitz,
Yinggan Zheng,
Alain CohenSolal,
Vojtěch Melenovský,
Jorge Escobedo,
Javed Butler,
Adrian F. Hernandez,
Carolyn S.P. Lam,
Christopher M. O’Connor,
Burkert Pieske,
Piotr Ponikowski,
Adriaan A. Voors,
Christopher R. deFilippi,
Cynthia M. Westerhout,
Ciaran J. McMullan,
Lothar Roessig,
Paul W. Armstrong
Publication year - 2021
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.121.056797
Subject(s) - medicine , anemia , hematocrit , hemoglobin , placebo , heart failure , adverse effect , randomization , anemia of chronic disease , surgery , randomized controlled trial , iron deficiency , pathology , alternative medicine
In the VICTORIA trial (Vericiguat Global Study in Patients with Heart Failure with Reduced Ejection Fraction), anemia occurred more often in patients treated with vericiguat (7.6%) than with placebo (5.7%). We explored the association between vericiguat, randomization hemoglobin, development of anemia, and whether the benefit of vericiguat related to baseline hemoglobin.
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