Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease | Zendy

Michael G. Levin | Zendy; Verena Zuber | Zendy; Venexia Walker | Zendy; Derek Klarin | Zendy; Julie A. Lynch | Zendy; Rainer Malik | Zendy; Aaron W. Aday | Zendy; Leonardo Bottolo | Zendy; Aruna D. Pradhan | Zendy; Martin Dichgans | Zendy; Kyong–Mi Chang | Zendy; Daniel J. Rader | Zendy; Philip S. Tsao | Zendy; Benjamin F. Voight | Zendy; Dipender Gill | Zendy; Stephen Burgess | Zendy; Scott M. Damrauer | Zendy

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Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease

Author(s) -

Michael G. Levin,

Verena Zuber,

Venexia Walker,

Derek Klarin,

Julie A. Lynch,

Rainer Malik,

Aaron W. Aday,

Leonardo Bottolo,

Aruna D. Pradhan,

Martin Dichgans,

Kyong–Mi Chang,

Daniel J. Rader,

Philip S. Tsao,

Benjamin F. Voight,

Dipender Gill,

Stephen Burgess,

Scott M. Damrauer

Publication year - 2021

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.121.053797

Subject(s) - mendelian randomization , medicine , lipoprotein , apolipoprotein b , odds ratio , lipoprotein(a) , risk factor , coronary artery disease , endocrinology , cholesterol , genetics , biology , gene , genotype , genetic variants

Lipoprotein-related traits have been consistently identified as risk factors for atherosclerotic cardiovascular disease, largely on the basis of studies of coronary artery disease (CAD). The relative contributions of specific lipoproteins to the risk of peripheral artery disease (PAD) have not been well defined. We leveraged large-scale genetic association data to investigate the effects of circulating lipoprotein-related traits on PAD risk.

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