Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program | Zendy

Derek Klarin | Zendy; Shefali S. Verma | Zendy; Renae Judy | Zendy; Ozan Dikilitas | Zendy; Brooke N. Wolford | Zendy; Ishan Paranjpe | Zendy; Michael G. Levin | Zendy; Cuiping Pan | Zendy; Catherine Tcheandjieu | Zendy; Joshua M. Spin | Zendy; Julie A. Lynch | Zendy; Themistocles L. Assimes | Zendy; Linn Åldstedt Nyrønning | Zendy; Erney Mattsson | Zendy; Todd L. Edwards | Zendy; Joshua C. Denny | Zendy; Eric B. Larson | Zendy; Ming Ta Michael Lee | Zendy; David Carrell | Zendy; Yanfei Zhang | Zendy; Gail P. Jarvik | Zendy; Ali G. Gharavi | Zendy; John B. Harley | Zendy; Frank Mentch | Zendy; Jennifer A. Pacheco | Zendy; Hákon Hákonarson | Zendy; Anne Heidi Skogholt | Zendy; Laurent F. Thomas | Zendy; Maiken E. Gabrielsen | Zendy; Kristian Hveem | Zendy; Jonas B. Nielsen | Zendy; Wei Zhou | Zendy; Lars G. Fritsche | Zendy; Jie Huang | Zendy; Pradeep Natarajan | Zendy; Yan V. Sun | Zendy; Scott L. DuVall | Zendy; Daniel J. Rader | Zendy; Kelly Cho | Zendy; Kyong–Mi Chang | Zendy; Peter W.F. Wilson | Zendy; Christopher J. O’Donnell | Zendy; Sekar Kathiresan | Zendy; Salvatore T. Scali | Zendy; Scott A. Berceli | Zendy; Cristen J. Willer | Zendy; Gregory T. Jones | Zendy; Matthew J. Bown | Zendy; Girish N. Nadkarni | Zendy; Iftikhar J. Kullo | Zendy; Marylyn D. Ritchie | Zendy; Scott M. Damrauer | Zendy; Philip S. Tsao | Zendy; J. Michael Gaziano | Zendy; Rachel Ramoni | Zendy; Jean C. Beckham | Zendy; Jim Breeling | Zendy; Grant D. Huang | Zendy; Sumitra Muralidhar | Zendy; Jonathan Romero | Zendy; Jennifer Moser | Zendy; Stacey B. Whitbourne | Zendy; Jessica V. Brewer | Zendy; John Concato | Zendy; Stuart Warren | Zendy; Dean P. Argyres | Zendy; Brady Stephens | Zendy; Mary T. Brophy | Zendy; Donald E. Humphries | Zendy; Nhan Do | Zendy; Shahpoor Shayan | Zendy; XuanMai T. Nguyen | Zendy; Saiju Pyarajan | Zendy; Elizabeth R. Hauser | Zendy; Hongyu Zhao | Zendy; Rachel McArdle | Zendy; Louis J. Dell’Italia | Zendy; Clement J. Zablocki | Zendy; Jeff Whittle | Zendy; John A. Wells | Zendy; Salvador Gutierrez | Zendy; Gretchen Gibson | Zendy; Laurence S. Kaminsky | Zendy; Gerardo Villareal | Zendy; Scott Kinlay | Zendy; Junzhe Xu | Zendy; Mark B. Hamner | Zendy; Kathlyn Sue Haddock | Zendy; Sujata Bhushan | Zendy; Pran Iruvanti | Zendy; Michael Godschalk | Zendy; Zuhair K. Ballas | Zendy; Malcolm Buford | Zendy; Stephen Mastorides | Zendy; Jon Klein | Zendy; Nora Ratcliffe | Zendy; Hermes Flórez | Zendy; Alan C. Swann | Zendy; Maureen Murdoch | Zendy; Peruvemba Sriram | Zendy; Shing Shing Yeh | Zendy; Ronald G. Washburn | Zendy; Darshana Jhala | Zendy; Samuel M. Aguayo | Zendy; David Cohen | Zendy; Satish Sharma | Zendy; John Callaghan | Zendy; Kris Ann Oursler | Zendy; Mary A. Whooley | Zendy; Sunil K. Ahuja | Zendy; Amparo Gutierrez | Zendy; Ronald Schifman | Zendy; Jennifer Greco | Zendy; Michael Rauchman | Zendy; Richard J. Servatius | Zendy; Mary E. Oehlert | Zendy; Agnes Wallbom | Zendy; Ronald Fernando | Zendy; Timothy R. Morgan | Zendy; Todd Stapley | Zendy; Scott E. Sherman | Zendy; Gwenevere Anderson | Zendy; Elif Sonel | Zendy; Edward J. Boyko | Zendy; Laurence Meyer | Zendy; Samir Gupta | Zendy; Joseph Fayad | Zendy; Adriana M. Hung | Zendy; Jack Lichy | Zendy; Robin A. Hurley | Zendy; R. Brooks Robey | Zendy; Rob Striker | Zendy

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Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

Author(s) -

Derek Klarin,

Shefali S. Verma,

Renae Judy,

Ozan Dikilitas,

Brooke N. Wolford,

Ishan Paranjpe,

Michael G. Levin,

Cuiping Pan,

Catherine Tcheandjieu,

Joshua M. Spin,

Julie A. Lynch,

Themistocles L. Assimes,

Linn Åldstedt Nyrønning,

Erney Mattsson,

Todd L. Edwards,

Joshua C. Denny,

Eric B. Larson,

Ming Ta Michael Lee,

David Carrell,

Yanfei Zhang,

Gail P. Jarvik,

Ali G. Gharavi,

John B. Harley,

Frank Mentch,

Jennifer A. Pacheco,

Hákon Hákonarson,

Anne Heidi Skogholt,

Laurent F. Thomas,

Maiken E. Gabrielsen,

Kristian Hveem,

Jonas B. Nielsen,

Wei Zhou,

Lars G. Fritsche,

Jie Huang,

Pradeep Natarajan,

Yan V. Sun,

Scott L. DuVall,

Daniel J. Rader,

Kelly Cho,

Kyong–Mi Chang,

Peter W.F. Wilson,

Christopher J. O’Donnell,

Sekar Kathiresan,

Salvatore T. Scali,

Scott A. Berceli,

Cristen J. Willer,

Gregory T. Jones,

Matthew J. Bown,

Girish N. Nadkarni,

Iftikhar J. Kullo,

Marylyn D. Ritchie,

Scott M. Damrauer,

Philip S. Tsao,

J. Michael Gaziano,

Rachel Ramoni,

Jean C. Beckham,

Jim Breeling,

Grant D. Huang,

Sumitra Muralidhar,

Jonathan Romero,

Jennifer Moser,

Stacey B. Whitbourne,

Jessica V. Brewer,

John Concato,

Stuart Warren,

Dean P. Argyres,

Brady Stephens,

Mary T. Brophy,

Donald E. Humphries,

Nhan Do,

Shahpoor Shayan,

XuanMai T. Nguyen,

Saiju Pyarajan,

Elizabeth R. Hauser,

Hongyu Zhao,

Rachel McArdle,

Louis J. Dell’Italia,

Clement J. Zablocki,

Jeff Whittle,

John A. Wells,

Salvador Gutierrez,

Gretchen Gibson,

Laurence S. Kaminsky,

Gerardo Villareal,

Scott Kinlay,

Junzhe Xu,

Mark B. Hamner,

Kathlyn Sue Haddock,

Sujata Bhushan,

Pran Iruvanti,

Michael Godschalk,

Zuhair K. Ballas,

Malcolm Buford,

Stephen Mastorides,

Jon Klein,

Nora Ratcliffe,

Hermes Flórez,

Alan C. Swann,

Maureen Murdoch,

Peruvemba Sriram,

Shing Shing Yeh,

Ronald G. Washburn,

Darshana Jhala,

Samuel M. Aguayo,

David Cohen,

Satish Sharma,

John Callaghan,

Kris Ann Oursler,

Mary A. Whooley,

Sunil K. Ahuja,

Amparo Gutierrez,

Ronald Schifman,

Jennifer Greco,

Michael Rauchman,

Richard J. Servatius,

Mary E. Oehlert,

Agnes Wallbom,

Ronald Fernando,

Timothy R. Morgan,

Todd Stapley,

Scott E. Sherman,

Gwenevere Anderson,

Elif Sonel,

Edward J. Boyko,

Laurence Meyer,

Samir Gupta,

Joseph Fayad,

Adriana M. Hung,

Jack Lichy,

Robin A. Hurley,

R. Brooks Robey,

Rob Striker

Publication year - 2020

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.120.047544

Subject(s) - mendelian randomization , medicine , odds ratio , genome wide association study , blood pressure , abdominal aortic aneurysm , population , heritability , genetic association , aneurysm , cardiology , genetics , surgery , genotype , single nucleotide polymorphism , biology , genetic variants , gene , environmental health

Abdominal aortic aneurysm (AAA) is an important cause of cardiovascular mortality; however, its genetic determinants remain incompletely defined. In total, 10 previously identified risk loci explain a small fraction of AAA heritability.

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