Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans
Author(s) -
Ásthildur Árnadóttir,
Sune Pedersen,
Rasmus Bo Hasselbalch,
Jens P. Goetze,
Lennart FriisHansen,
AnnaMarie Bloch Münster,
Jan Skov Jensen,
Henning Bundgaard,
Kasper Iversen
Publication year - 2020
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.120.046574
Subject(s) - medicine , copeptin , cardiology , myocardial infarction , ischemia , interquartile range , troponin t , coronary artery disease , troponin i , vasopressin
Cardiac troponins (cTns) are the cornerstone of diagnosing acute myocardial infarction. There is limited knowledge on the duration of ischemia necessary to induce a measurable release of cTns or the very-early-release kinetics of cTns after an ischemic event. Copeptin may have a supplementary role in ruling out myocardial infarction early. We investigated the release of cTns and copeptin in the first hours after experimental balloon-induced ischemia in humans.
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