Results of the FUEL Trial | Zendy

David Goldberg | Zendy; Victor Zak | Zendy; Bryan H. Goldstein | Zendy; Kurt R. Schumacher | Zendy; Jonathan Rhodes | Zendy; Daniel J. Penny | Zendy; Christopher J. Petit | Zendy; Salil Ginde | Zendy; Shaji C. Me | Zendy; Seong Ho Kim | Zendy; Gi Beom Kim | Zendy; Todd Nowlen | Zendy; Michael V. DiMaria | Zendy; Benjamin P. Frischhertz | Zendy; Jonathan Wagner | Zendy; Kimberly E. McHugh | Zendy; Brian W. McCrindle | Zendy; Amanda J. Shillingford | Zendy; Arash Sabati | Zendy; Anji T. Yetman | Zendy; Anitha S. John | Zendy; Marc E. Richmond | Zendy; Matthew D. Files | Zendy; R. Mark Payne | Zendy; Andrew S. Mackie | Zendy; Christopher K. Davis | Zendy; Shabana Shahanavaz | Zendy; Kevin D. Hill | Zendy; Ruchira Garg | Zendy; Jeffrey P. Jacobs | Zendy; Michelle Hamstra | Zendy; Stacy Woyciechowski | Zendy; Kathleen A. Rathge | Zendy; Michael G. McBride | Zendy; Peter C. Frommelt | Zendy; Mark W. Russell | Zendy; Elaine M. Urbina | Zendy; James L. Yeager | Zendy; Victoria L. Pemberton | Zendy; Mario Stylianou | Zendy; Gail D. Pearson | Zendy; Stephen M. Paridon | Zendy

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Results of the FUEL Trial

Author(s) -

David Goldberg,

Victor Zak,

Bryan H. Goldstein,

Kurt R. Schumacher,

Jonathan Rhodes,

Daniel J. Penny,

Christopher J. Petit,

Salil Ginde,

Shaji C. Me,

Seong Ho Kim,

Gi Beom Kim,

Todd Nowlen,

Michael V. DiMaria,

Benjamin P. Frischhertz,

Jonathan Wagner,

Kimberly E. McHugh,

Brian W. McCrindle,

Amanda J. Shillingford,

Arash Sabati,

Anji T. Yetman,

Anitha S. John,

Marc E. Richmond,

Matthew D. Files,

R. Mark Payne,

Andrew S. Mackie,

Christopher K. Davis,

Shabana Shahanavaz,

Kevin D. Hill,

Ruchira Garg,

Jeffrey P. Jacobs,

Michelle Hamstra,

Stacy Woyciechowski,

Kathleen A. Rathge,

Michael G. McBride,

Peter C. Frommelt,

Mark W. Russell,

Elaine M. Urbina,

James L. Yeager,

Victoria L. Pemberton,

Mario Stylianou,

Gail D. Pearson,

Stephen M. Paridon

Publication year - 2019

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.119.044352

Subject(s) - medicine , pharmacotherapy , intensive care medicine , clinical trial , vascular resistance , circulation (fluid dynamics) , fontan procedure , cardiology , hemodynamics , heart disease , physics , thermodynamics

The Fontan operation creates a total cavopulmonary connection, a circulation in which the importance of pulmonary vascular resistance is magnified. Over time, this circulation leads to deterioration of cardiovascular efficiency associated with a decline in exercise performance. Rigorous clinical trials aimed at improving physiology and guiding pharmacotherapy are lacking.

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