Comparison of Events Across Bleeding Scales in the ENGAGE AF-TIMI 48 Trial
Author(s) -
Brian A. Bergmark,
Pieter W. Kamphuisen,
Stephen D. Wiviott,
Christian T. Ruff,
Elliott M. Antman,
Francesco Nordio,
Julia Kuder,
Michele Mercuri,
Hans Lanz,
Eugene Braunwald,
Robert P. Giugliano
Publication year - 2019
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.119.041346
Subject(s) - timi , medicine , cardiology , myocardial infarction , percutaneous coronary intervention
Numerous scales exist for the classification of major bleeding events. Limited data compare the most commonly used bleeding scales within a single at-risk cohort of patients with atrial fibrillation. Here, we analyze bleeding outcomes according to the ISTH (International Society on Thrombosis and Hemostasis), TIMI (Thrombolysis in Myocardial Infarction), GUSTO (Global Usage of Strategies to Open Occluded Arteries), and BARC (Bleeding Academic Research Consortium) bleeding scales in the ENGAGE AF (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation)-TIMI 48 trial (NCT00781391) of edoxaban versus warfarin.
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