Patients With Atrial Fibrillation Taking Nonsteroidal Anti-Inflammatory Drugs and Oral Anticoagulants in the ARISTOTLE Trial | Zendy

Frederik Dalgaard | Zendy; Hillary Mulder | Zendy; Daniel Wojdyla | Zendy; Renato D. Lópes | Zendy; Claes Held | Zendy; John H. Alexander | Zendy; Raffaele De Caterina | Zendy; Jeffrey B. Washam | Zendy; Elaine M. Hylek | Zendy; David García | Zendy; Bernard J. Gersh | Zendy; Lars Wallentin | Zendy; Christopher B. Granger | Zendy; Sana M. AlKhatib | Zendy

Open Access

Patients With Atrial Fibrillation Taking Nonsteroidal Anti-Inflammatory Drugs and Oral Anticoagulants in the ARISTOTLE Trial

Author(s) -

Frederik Dalgaard,

Hillary Mulder,

Daniel Wojdyla,

Renato D. Lópes,

Claes Held,

John H. Alexander,

Raffaele De Caterina,

Jeffrey B. Washam,

Elaine M. Hylek,

David García,

Bernard J. Gersh,

Lars Wallentin,

Christopher B. Granger,

Sana M. AlKhatib

Publication year - 2019

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.119.041296

Subject(s) - medicine , apixaban , atrial fibrillation , warfarin , stroke (engine) , rivaroxaban , randomized controlled trial , gastrointestinal bleeding , lower risk , hazard ratio , cardiology , confidence interval , mechanical engineering , engineering

The use of nonsteroidal anti-inflammatory drugs (NSAIDs) with oral anticoagulants has been associated with an increased risk of bleeding. We investigated the risk of bleeding and major cardiovascular outcomes in patients with atrial fibrillation taking NSAIDs and apixaban or warfarin.

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