Unlocking the Secrets of Mitochondria in the Cardiovascular System | Zendy

Rong Tian | Zendy; Wilson S. Colucci | Zendy; Zoltàn Arany | Zendy; Markus Bachschmid | Zendy; Scott W. Ballinger | Zendy; Sihem Boudina | Zendy; James E. Bruce | Zendy; David W. Busija | Zendy; Sergey Dikalov | Zendy; Gerald W. Dorn | Zendy; Zorina S. Galis | Zendy; Roberta A. Gottlieb | Zendy; Daniel P. Kelly | Zendy; Richard N. Kitsis | Zendy; Mark J. Kohr | Zendy; Daniel Levy | Zendy; E. Douglas Lewandowski | Zendy; Joseph M. McClung | Zendy; Daria MochlyRosen | Zendy; Kevin D. O’Brien | Zendy; Brian O’Rourke | Zendy; JoonYoung Park | Zendy; Peipei Ping | Zendy; Michael N. Sack | Zendy; SheyShing Sheu | Zendy; Yang Shi | Zendy; Sruti Shiva | Zendy; Douglas C. Wallace | Zendy; Robert G. Weiss | Zendy; Hilary J. Ver | Zendy; Renee Wong | Zendy; Lisa Schwartz Longacre | Zendy; Scarlet Shi | Zendy

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Unlocking the Secrets of Mitochondria in the Cardiovascular System

Author(s) -

Rong Tian,

Wilson S. Colucci,

Zoltàn Arany,

Markus Bachschmid,

Scott W. Ballinger,

Sihem Boudina,

James E. Bruce,

David W. Busija,

Sergey Dikalov,

Gerald W. Dorn,

Zorina S. Galis,

Roberta A. Gottlieb,

Daniel P. Kelly,

Richard N. Kitsis,

Mark J. Kohr,

Daniel Levy,

E. Douglas Lewandowski,

Joseph M. McClung,

Daria MochlyRosen,

Kevin D. O’Brien,

Brian O’Rourke,

JoonYoung Park,

Peipei Ping,

Michael N. Sack,

SheyShing Sheu,

Yang Shi,

Sruti Shiva,

Douglas C. Wallace,

Robert G. Weiss,

Hilary J. Ver,

Renee Wong,

Lisa Schwartz Longacre,

Scarlet Shi

Publication year - 2019

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.119.040551

Subject(s) - medicine , heart failure , mitochondrion , translational research , intensive care medicine , pathogenesis , bioinformatics , cardiology , pathology , biology , microbiology and biotechnology

Mitochondria have emerged as a central factor in the pathogenesis and progression of heart failure, and other cardiovascular diseases, as well, but no therapies are available to treat mitochondrial dysfunction. The National Heart, Lung, and Blood Institute convened a group of leading experts in heart failure, cardiovascular diseases, and mitochondria research in August 2018. These experts reviewed the current state of science and identified key gaps and opportunities in basic, translational, and clinical research focusing on the potential of mitochondria-based therapeutic strategies in heart failure. The workshop provided short- and long-term recommendations for moving the field toward clinical strategies for the prevention and treatment of heart failure and cardiovascular diseases by using mitochondria-based approaches.

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