Open AccessDonor Simvastatin Treatment in Heart Transplantation
Author(s) -
Antti I. Nykänen,
E. Holmström,
Raimo Tuuminen,
R. Krebs,
Kishor Dhaygude,
Matti Kankainen,
Janne J. Jokinen,
Jyri Lommi,
Ilkka Helanterä,
Anne RäisänenSokolowski,
S. Syrjälä,
Karl Lemström
Publication year - 2019
Publication title -
circulation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.119.039932
Subject(s) - medicine , simvastatin , heart transplantation , transplantation , cardiology
Ischemia-reperfusion injury may compromise the short-term and long-term prognosis after heart transplantation. Experimental studies show that simvastatin administered to the organ donor is vasculoprotective and inhibits cardiac allograft ischemia-reperfusion injury.
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