Conserved NPPB + Border Zone Switches From MEF2- to AP-1–Driven Gene Program | Zendy

Karel van Duijvenboden | Zendy; Dennis E. M. de Bakker | Zendy; Joyce C.K. Man | Zendy; Rob Janssen | Zendy; Marie Günthel | Zendy; Matthew C. Hill | Zendy; Ingeborg B. Hooijkaas | Zendy; Ingeborg van der Made | Zendy; Petra H. van der Kraak | Zendy; Aryan Vink | Zendy; Esther E. Creemers | Zendy; James F. Martin | Zendy; Phil Barnett | Zendy; Jeroen Bakkers | Zendy; Vincent M. Christoffels | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Conserved NPPB + Border Zone Switches From MEF2- to AP-1–Driven Gene Program

Author(s) -

Karel van Duijvenboden,

Dennis E. M. de Bakker,

Joyce C.K. Man,

Rob Janssen,

Marie Günthel,

Matthew C. Hill,

Ingeborg B. Hooijkaas,

Ingeborg van der Made,

Petra H. van der Kraak,

Aryan Vink,

Esther E. Creemers,

James F. Martin,

Phil Barnett,

Jeroen Bakkers,

Vincent M. Christoffels

Publication year - 2019

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.118.038944

Subject(s) - border zone , myocardial infarction , medicine , chromatin , biology , microbiology and biotechnology , gene , genetics

Surviving cells in the postinfarction border zone are subjected to intense fluctuations of their microenvironment. Recently, border zone cardiomyocytes have been specifically implicated in cardiac regeneration. Here, we defined their unique transcriptional and regulatory properties, and comprehensively validated new molecular markers, including Nppb, encoding B-type natriuretic peptide, after infarction.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research