Angiotensin Receptor Neprilysin Inhibitor for Functional Mitral Regurgitation | Zendy

DukHyun Kang | Zendy; SungJi Park | Zendy; SungHee Shin | Zendy; GeuRu Hong | Zendy; Sahmin Lee | Zendy; MinSeok Kim | Zendy; SungCheol Yun | Zendy; JongMin Song | Zendy; Seung Woo Park | Zendy; JaeJoong Kim | Zendy

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Angiotensin Receptor Neprilysin Inhibitor for Functional Mitral Regurgitation

Author(s) -

DukHyun Kang,

SungJi Park,

SungHee Shin,

GeuRu Hong,

Sahmin Lee,

MinSeok Kim,

SungCheol Yun,

JongMin Song,

Seung Woo Park,

JaeJoong Kim

Publication year - 2019

Publication title -

circulation

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.118.037077

Subject(s) - valsartan , medicine , sacubitril , cardiology , ejection fraction , mitral regurgitation , heart failure , sacubitril, valsartan , angiotensin ii , blood pressure

The morbidity and mortality of patients with functional mitral regurgitation (MR) remain high, but no pharmacological therapy has been proven effective. The hypothesis of this study was that sacubitril/valsartan would be superior to valsartan alone in improving functional MR via dual inhibition of the renin-angiotensin system and neprilysin.

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