Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis | Zendy

Shuin Park | Zendy; Sara Ranjbarvaziri | Zendy; Fides D. Lay | Zendy; Peng Zhao | Zendy; Mark J. Miller | Zendy; Jasmeet Dhaliwal | Zendy; Adriana HuertasVázquez | Zendy; Xiuju Wu | Zendy; Rong Qiao | Zendy; Justin M. Soffer | Zendy; Christoph Rau | Zendy; Yibin Wang | Zendy; Hanna Mikkola | Zendy; Aldons J. Lusis | Zendy; Reza Ardehali | Zendy

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Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis

Author(s) -

Shuin Park,

Sara Ranjbarvaziri,

Fides D. Lay,

Peng Zhao,

Mark J. Miller,

Jasmeet Dhaliwal,

Adriana HuertasVázquez,

Xiuju Wu,

Rong Qiao,

Justin M. Soffer,

Christoph Rau,

Yibin Wang,

Hanna Mikkola,

Aldons J. Lusis,

Reza Ardehali

Publication year - 2018

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.118.035420

Subject(s) - cardiac fibrosis , fibrosis , fibroblast , medicine , in vivo , gene expression , microbiology and biotechnology , immunohistochemistry , masson's trichrome stain , gene knockdown , cardiac function curve , andrology , in vitro , gene , pathology , biology , biochemistry , heart failure , genetics

Genetic diversity and the heterogeneous nature of cardiac fibroblasts (CFbs) have hindered characterization of the molecular mechanisms that regulate cardiac fibrosis. The Hybrid Mouse Diversity Panel offers a valuable tool to examine genetically diverse cardiac fibroblasts and their role in fibrosis.

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