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Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy
Author(s) -
Carolyn Y. Ho,
Sharlene M. Day,
Euan A. Ashley,
Michelle Michels,
Alexandre C. Pereira,
Daniel Jacoby,
Allison L. Cirino,
Jonathan C. Fox,
Neal K. Lakdawala,
James S. Ware,
Colleen Caleshu,
Adam Helms,
Steven D. Colan,
Francesca Girolami,
Franco Cecchi,
Christine E. Seidman,
Gautam Sajeev,
James Signorovitch,
Eric M. Green,
Iacopo Olivotto
Publication year - 2018
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.117.033200
Subject(s) - medicine , interquartile range , hypertrophic cardiomyopathy , atrial fibrillation , implantable cardioverter defibrillator , cardiomyopathy , sudden cardiac death , cardiology , population , restrictive cardiomyopathy , fabry disease , ejection fraction , left ventricular hypertrophy , disease , pediatrics , heart failure , blood pressure , environmental health
A better understanding of the factors that contribute to heterogeneous outcomes and lifetime disease burden in hypertrophic cardiomyopathy (HCM) is critically needed to improve patient management and outcomes. The Sarcomeric Human Cardiomyopathy Registry (SHaRe) was established to provide the scale of data required to address these issues, aggregating longitudinal datasets curated by eight international HCM specialty centers.

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