Impact of Novel Low-Density Lipoprotein-Cholesterol Assessment on the Utility of Secondary Non-High-Density Lipoprotein-C and Apolipoprotein B Targets in Selected Worldwide Dyslipidemia Guidelines
Author(s) -
Vasanth Sathiyakumar,
Jihwan Park,
Renato Quispe,
Mohamed B. Elshazly,
Erin D. Michos,
Maciej Banach,
Peter P. Tóth,
Seamus P. Whelton,
Roger S. Blumenthal,
Steven R. Jones,
Seth S. Martin
Publication year - 2018
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.117.032463
Subject(s) - apolipoprotein b , dyslipidemia , medicine , guideline , lipoprotein , diabetes mellitus , population , cholesterol , metabolic syndrome , national health and nutrition examination survey , endocrinology , gastroenterology , pathology , environmental health
Selected dyslipidemia guidelines recommend non-high-density lipoprotein-cholesterol (non-HDL-C) and apolipoprotein B (apoB) as secondary targets to the primary target of low-density lipoprotein-cholesterol (LDL-C). After considering 2 LDL-C estimates that differ in accuracy, we examined: (1) how frequently non-HDL-C guideline targets could change management; and (2) the utility of apoB targets after meeting LDL-C and non-HDL-C targets.
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