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Combining High-Sensitivity Cardiac Troponin I and Cardiac Troponin T in the Early Diagnosis of Acute Myocardial Infarction
Author(s) -
Noreen van der Linden,
Karin Wildi,
Raphael Twerenbold,
John W. Pickering,
Martin Than,
Louise Cullen,
Jaimi Greenslade,
William Parsonage,
Thomas Nestelberger,
Jasper Boeddinghaus,
Patrick Badertscher,
María Rubini Giménez,
Lieke J.J. Klinkenberg,
Otto Bekers,
Aline A. Schöni,
Dagmar I. Keller,
Zaid Sabti,
Christian Puelacher,
Janosch Cupa,
Lukas Schumacher,
Nikola Kozhuharov,
Karin Grimm,
Samyut Shrestha,
Dayana Flores,
Michael Freese,
Claudia Stelzig,
Ivo Strebel,
Òscar Miró,
Katharina Rentsch,
Beata Morawiec,
Damian Kawecki,
Wanda Kloos,
Jens Lohrmann,
Mark Richards,
Richard W. Troughton,
Chris Frampton,
Stefan Osswald,
Marja P. van DieijenVisser,
Alma M.A. Mingels,
Tobias Reichlin,
Steven J.R. Meex,
Christian Mueller
Publication year - 2018
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.117.032003
Subject(s) - medicine , myocardial infarction , cardiology , troponin complex , troponin i , troponin , diagnostic accuracy , roche diagnostics , blood sampling , guideline , pathology
Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a single blood draw. We aimed to evaluate the diagnostic performance of combinations of high-sensitivity (hs) cTnI and hs-cTnT for the early diagnosis of acute myocardial infarction.

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