Tryptophan-Derived 3-Hydroxyanthranilic Acid Contributes to Angiotensin II–Induced Abdominal Aortic Aneurysm Formation in Mice In Vivo | Zendy

Qiongxin Wang | Zendy; Ding Ye | Zendy; Ping Song | Zendy; Huaiping Zhu | Zendy; Imoh S. Okon | Zendy; Yang-Nan Ding | Zendy; HouZao Chen | Zendy; DePei Liu | Zendy; Ming-Hui Zou | Zendy

Open Access

Tryptophan-Derived 3-Hydroxyanthranilic Acid Contributes to Angiotensin II–Induced Abdominal Aortic Aneurysm Formation in Mice In Vivo

Author(s) -

Qiongxin Wang,

Ding Ye,

Ping Song,

Huaiping Zhu,

Imoh S. Okon,

Yang-Nan Ding,

HouZao Chen,

DePei Liu,

Ming-Hui Zou

Publication year - 2017

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.117.030972

Subject(s) - medicine , abdominal aortic aneurysm , in vivo , angiotensin ii , aortic aneurysm , tryptophan , renin–angiotensin system , endocrinology , pharmacology , aneurysm , surgery , aorta , biochemistry , receptor , amino acid , biology , genetics , blood pressure

Abnormal amino acid metabolism is associated with vascular disease. However, the causative link between dysregulated tryptophan metabolism and abdominal aortic aneurysm (AAA) is unknown.

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