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NT-proBNP (N-Terminal pro-B-Type Natriuretic Peptide)-Guided Therapy in Acute Decompensated Heart Failure
Author(s) -
Susan Stienen,
Khibar Salah,
Arno H. Moons,
Adrianus L. M. Bakx,
Petra van Pol,
R. A. Mikael Kortz,
João Pedro Ferreira,
Irene Marques,
Jutta M. SchroederTanka,
J. Keijer,
Antoni BayésGenís,
Jan G.P. Tijssen,
Yigal M. Pinto,
Wouter E.M. Kok
Publication year - 2017
Publication title -
circulation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.117.029882
Subject(s) - medicine , natriuretic peptide , acute decompensated heart failure , heart failure , clinical endpoint , cardiology , randomized controlled trial
The concept of natriuretic peptide guidance has been extensively studied in patients with chronic heart failure (HF), with only limited success. The effect of NT-proBNP (N-terminal probrain natriuretic peptide)-guided therapy in patients with acute decompensated HF using a relative NT-proBNP target has not been investigated. This study aimed to assess whether NT-proBNP-guided therapy of patients with acute decompensated HF using a relative NT-proBNP target would lead to improved outcomes compared with conventional therapy.

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