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Prospective Study of Adenosine on Atrioventricular Nodal Conduction in Pediatric and Young Adult Patients After Heart Transplantation
Author(s) -
Jonathan N. Flyer,
Warren A. Zuckerman,
Marc E. Richmond,
Brett R. Anderson,
Tamar G. Mendelsberg,
J. McAllister,
Leonardo Liberman,
Linda J. Addonizio,
Eric S. Silver
Publication year - 2017
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.117.028087
Subject(s) - medicine , adenosine , nodal , cardiology , transplantation , heart transplantation , prospective cohort study
Supraventricular tachycardia is common after heart transplantation. Adenosine, the standard therapy for treating supraventricular tachycardia in children and adults without transplantation, is relatively contraindicated after transplantation because of a presumed risk of prolonged atrioventricular block in denervated hearts. This study tested whether adenosine caused prolonged asystole after transplantation and if it was effective in blocking atrioventricular nodal conduction in these patients.

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