Anti-Müllerian Hormone Trajectories Are Associated With Cardiovascular Disease in Women | Zendy

Annelien C. de Kat | Zendy; W. M. Monique Verschuren | Zendy; Marinus J.C. Eijkemans | Zendy; Frank J. Broekmans | Zendy; Yvonne T. van der Schouw | Zendy

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Anti-Müllerian Hormone Trajectories Are Associated With Cardiovascular Disease in Women

Author(s) -

Annelien C. de Kat,

W. M. Monique Verschuren,

Marinus J.C. Eijkemans,

Frank J. Broekmans,

Yvonne T. van der Schouw

Publication year - 2017

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.116.025968

Subject(s) - medicine , hazard ratio , body mass index , menopause , stroke (engine) , confidence interval , population , cohort , cohort study , disease , cardiology , gynecology , mechanical engineering , environmental health , engineering

Earlier age at menopause is widely considered to be associated with an increased risk of cardiovascular disease. However, the underlying mechanisms of this relationship remain undetermined. Indications suggest that anti-Müllerian hormone (AMH), an ovarian reserve marker, plays a physiological role outside of the reproductive system. Therefore, we investigated whether longitudinal AMH decline trajectories are associated with an increased risk of cardiovascular disease (CVD) occurrence.

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