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Recurrent Hospitalization Among Patients With Atrial Fibrillation Undergoing Intracoronary Stenting Treated With 2 Treatment Strategies of Rivaroxaban or a Dose-Adjusted Oral Vitamin K Antagonist Treatment Strategy
Author(s) -
C. Michael Gibson,
Duane S. Pinto,
Gerald Chi,
Douglas Arbetter,
Megan K. Yee,
Roxana Mehran,
Christoph Bode,
Jonathan L. Halperin,
Freek W.A. Verheugt,
Peter Wildgoose,
Paul Burton,
Martin van Eickels,
Serge Korjian,
Yazan Daaboul,
Purva Jain,
Gregory Y.H. Lip,
Marc Cohen,
Eric D. Peterson,
Keith A.A. Fox
Publication year - 2016
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.116.025783
Subject(s) - medicine , rivaroxaban , atrial fibrillation , vitamin k antagonist , hazard ratio , confidence interval , clinical endpoint , cardiology , warfarin , randomized controlled trial
Patients with atrial fibrillation who undergo intracoronary stenting traditionally are treated with a vitamin K antagonist (VKA) plus dual antiplatelet therapy (DAPT), yet this treatment leads to high risks of bleeding. We hypothesized that a regimen of rivaroxaban plus a P2Y 12 inhibitor monotherapy or rivaroxaban plus DAPT could reduce bleeding and thereby have a favorable impact on all-cause mortality and the need for rehospitalization.

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