Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease | Zendy

Emerson C. Perin | Zendy; Michael P. Murphy | Zendy; Keith L. March | Zendy; Roberto Bolli | Zendy; John Loughran | Zendy; Phillip C. Yang | Zendy; Nicholas J. Leeper | Zendy; Ronald L. Dalman | Zendy; Jason Alexander | Zendy; Timothy D. Henry | Zendy; Jay H. Traverse | Zendy; Carl J. Pepine | Zendy; R. David Anderson | Zendy; Scott A. Berceli | Zendy; James T. Willerson | Zendy; Raja Muthupillai | Zendy; Amir Gahremanpour | Zendy; Ganesh Raveendran | Zendy; Omaida Velasquez | Zendy; Joshua M. Hare | Zendy; Ivonne Hernandez Schulman | Zendy; Vijaykumar S. Kasi | Zendy; William R. Hiatt | Zendy; Bharath AmbaleVenkatesh | Zendy; João A.C. Lima | Zendy; Doris A. Taylor | Zendy; Micheline Resende | Zendy; Adrian P. Gee | Zendy; April Durett | Zendy; Jeanette Bloom | Zendy; Sara Richman | Zendy; Patricia G’Sell | Zendy; Shari Williams | Zendy; Fouzia Khan | Zendy; Elsie Gyang Ross | Zendy; Michelle Santoso | Zendy; JoAnne Goldman | Zendy; Dana Leach | Zendy; Eileen Handberg | Zendy; Benjamin Cheong | Zendy; Nichole Piece | Zendy; Darcy L. DiFede | Zendy; Barb Bruhn-Ding | Zendy; Emily Caldwell | Zendy; Judy Bettencourt | Zendy; Dejian Lai | Zendy; Linda B. Piller | Zendy; Lara M. Simpson | Zendy; Michelle Cohen | Zendy; Shelly L. Sayre | Zendy; Rachel W. Vojvodic | Zendy; Lem Moyé | Zendy; Ray F. Ebert | Zendy; Robert D. Simari | Zendy; Alan T. Hirsch | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease

Author(s) -

Emerson C. Perin,

Michael P. Murphy,

Keith L. March,

Roberto Bolli,

John Loughran,

Phillip C. Yang,

Nicholas J. Leeper,

Ronald L. Dalman,

Jason Alexander,

Timothy D. Henry,

Jay H. Traverse,

Carl J. Pepine,

R. David Anderson,

Scott A. Berceli,

James T. Willerson,

Raja Muthupillai,

Amir Gahremanpour,

Ganesh Raveendran,

Omaida Velasquez,

Joshua M. Hare,

Ivonne Hernandez Schulman,

Vijaykumar S. Kasi,

William R. Hiatt,

Bharath AmbaleVenkatesh,

João A.C. Lima,

Doris A. Taylor,

Micheline Resende,

Adrian P. Gee,

April Durett,

Jeanette Bloom,

Sara Richman,

Patricia G’Sell,

Shari Williams,

Fouzia Khan,

Elsie Gyang Ross,

Michelle Santoso,

JoAnne Goldman,

Dana Leach,

Eileen Handberg,

Benjamin Cheong,

Nichole Piece,

Darcy L. DiFede,

Barb Bruhn-Ding,

Emily Caldwell,

Judy Bettencourt,

Dejian Lai,

Linda B. Piller,

Lara M. Simpson,

Michelle Cohen,

Shelly L. Sayre,

Rachel W. Vojvodic,

Lem Moyé,

Ray F. Ebert,

Robert D. Simari,

Alan T. Hirsch

Publication year - 2017

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.116.025707

Subject(s) - medicine , peripheral , arterial disease , perfusion , cardiology , disease , vascular disease , physical therapy

Atherosclerotic peripheral artery disease affects 8% to 12% of Americans >65 years of age and is associated with a major decline in functional status, increased myocardial infarction and stroke rates, and increased risk of ischemic amputation. Current treatment strategies for claudication have limitations. PACE (Patients With Intermittent Claudication Injected With ALDH Bright Cells) is a National Heart, Lung, and Blood Institute-sponsored, randomized, double-blind, placebo-controlled, phase 2 exploratory clinical trial designed to assess the safety and efficacy of autologous bone marrow-derived aldehyde dehydrogenase bright (ALDHbr) cells in patients with peripheral artery disease and to explore associated claudication physiological mechanisms.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research