Open AccessMediterranean Diet Improves High-Density Lipoprotein Function in High-Cardiovascular-Risk Individuals
Author(s) -
Álvaro Hernáez,
Olga Castañer,
Roberto Elosúa,
Xavier Pintó,
Ramón Estruch,
Jordi SalasSalvadó,
Dolores Corella,
Fernando Arós,
Lluís SerraMajem,
Miquel Fiol,
Manuel OrtegaCalvo,
Emilio Ros,
Miguel Ángel MartínezGonzález,
Rafael de la Torre,
M. Carmen LópezSabater,
Montserrat Fitó
Publication year - 2017
Publication title -
circulation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.116.023712
Subject(s) - paraoxonase , pon1 , medicine , cholesterol , mediterranean diet , antioxidant , high density lipoprotein , cholesterylester transfer protein , lipoprotein , endocrinology , reverse cholesterol transport , apolipoprotein b , biochemistry , oxidative stress , biology , genotype , gene
The biological functions of high-density lipoproteins (HDLs) contribute to explaining the cardioprotective role of the lipoprotein beyond quantitative HDL cholesterol levels. A few small-scale interventions with a single antioxidant have improved some HDL functions. However, to date, no long-term, large-scale, randomized controlled trial has been conducted to assess the effects of an antioxidant-rich dietary pattern (such as a traditional Mediterranean diet [TMD]) on HDL function in humans.
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