Detailed Echocardiographic Phenotyping in Breast Cancer Patients
Author(s) -
Hari K. Narayan,
Brian S. Finkelman,
Benjamin French,
Theodore Plappert,
David M. Hyman,
Amanda M. Smith,
Kenneth B. Margulies,
Bonnie Ky
Publication year - 2017
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.116.023463
Subject(s) - medicine , breast cancer , cancer , oncology
Cardiovascular disease in patients with breast cancer is of growing concern. The longitudinal effects of commonly used therapies, including doxorubicin and trastuzumab, on cardiac remodeling and function remain unknown in this population. We aimed to define the changes in echocardiographic parameters of structure, function, and ventricular-arterial coupling, and their associations with left ventricular ejection fraction (LVEF) and heart failure symptoms.
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