Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention | Zendy

Sanjoy K. Chowdhury | Zendy; Wei Liu | Zendy; Min Zi | Zendy; Yatong Li | Zendy; Shunyao Wang | Zendy; Hoyee Tsui | Zendy; Sukhpal Prehar | Zendy; Simon J. Castro | Zendy; Henggui Zhang | Zendy; Yong Ji | Zendy; Xiuqin Zhang | Zendy; RuiPing Xiao | Zendy; Rongli Zhang | Zendy; Ming Lei | Zendy; Lukas Cyganek | Zendy; Kaomei Guan | Zendy; Catherine B. Millar | Zendy; Xudong Liao | Zendy; Mukesh K. Jain | Zendy; Mark R. Boyett | Zendy; Elizabeth J. Cartwright | Zendy; Holly A. Shiels | Zendy; Xin Wang | Zendy

Open Access

Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention

Author(s) -

Sanjoy K. Chowdhury,

Wei Liu,

Min Zi,

Yatong Li,

Shunyao Wang,

Hoyee Tsui,

Sukhpal Prehar,

Simon J. Castro,

Henggui Zhang,

Yong Ji,

Xiuqin Zhang,

RuiPing Xiao,

Rongli Zhang,

Ming Lei,

Lukas Cyganek,

Kaomei Guan,

Catherine B. Millar,

Xudong Liao,

Mukesh K. Jain,

Mark R. Boyett,

Elizabeth J. Cartwright,

Holly A. Shiels,

Xin Wang

Publication year - 2016

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.116.022941

Subject(s) - protein kinase a , ask1 , histone deacetylase , map kinase kinase kinase , histone deacetylase 5 , medicine , kinase , microbiology and biotechnology , histone deacetylase inhibitor , cancer research , mitogen activated protein kinase kinase , pharmacology , biology , histone , biochemistry , gene

Ventricular arrhythmia is a leading cause of cardiac mortality. Most antiarrhythmics present paradoxical proarrhythmic side effects, culminating in a greater risk of sudden death.

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