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L-type calcium channels (LTCCs) play important roles in regulating cardiomyocyte physiology, which is governed by appropriate LTCC trafficking to and density at the cell surface. Factors influencing the expression, half-life, subcellular trafficking, and gating of LTCCs are therefore critically involved in conditions of cardiac physiology and disease.

Peptidomimetic Targeting of Ca v β2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function

Peptidomimetic Targeting of Ca _v β2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function