Smooth Muscle Enriched Long Noncoding RNA ( SMILR ) Regulates Cell Proliferation | Zendy

Margaret D. Ballantyne | Zendy; Karine Pinel | Zendy; Rachel Dakin | Zendy; Alex Vesey | Zendy; Louise A Diver | Zendy; Ruth M. Mackenzie | Zendy; Raquel García | Zendy; Paul Welsh | Zendy; Naveed Sattar | Zendy; Graham Hamilton | Zendy; Nikhil Joshi | Zendy; Marc R. Dweck | Zendy; Joseph M. Miano | Zendy; Martin McBride | Zendy; David E. Newby | Zendy; Robert A. McDonald | Zendy; Andrew H. Baker | Zendy

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Smooth Muscle Enriched Long Noncoding RNA ( SMILR ) Regulates Cell Proliferation

Author(s) -

Margaret D. Ballantyne,

Karine Pinel,

Rachel Dakin,

Alex Vesey,

Louise A Diver,

Ruth M. Mackenzie,

Raquel García,

Paul Welsh,

Naveed Sattar,

Graham Hamilton,

Nikhil Joshi,

Marc R. Dweck,

Joseph M. Miano,

Martin McBride,

David E. Newby,

Robert A. McDonald,

Andrew H. Baker

Publication year - 2016

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.115.021019

Subject(s) - vascular smooth muscle , gene knockdown , cell growth , microbiology and biotechnology , rna interference , cell , stimulation , gene expression , growth factor , medicine , cytoplasm , myocyte , rna , biology , cancer research , endocrinology , gene , smooth muscle , receptor , biochemistry

Phenotypic switching of vascular smooth muscle cells from a contractile to a synthetic state is implicated in diverse vascular pathologies, including atherogenesis, plaque stabilization, and neointimal hyperplasia. However, very little is known about the role of long noncoding RNA (lncRNA) during this process. Here, we investigated a role for lncRNAs in vascular smooth muscle cell biology and pathology.

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