Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure | Zendy

Akihiro Shirakabe | Zendy; Peiyong Zhai | Zendy; Yoshiyuki Ikeda | Zendy; Toshiro Saito | Zendy; Yasuhiro Maejima | Zendy; ChiaoPo Hsu | Zendy; Masatoshi Nomura | Zendy; Kensuke Egashira | Zendy; Beth Levine | Zendy; Junichi Sadoshima | Zendy

Open Access

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure

Author(s) -

Akihiro Shirakabe,

Peiyong Zhai,

Yoshiyuki Ikeda,

Toshiro Saito,

Yasuhiro Maejima,

ChiaoPo Hsu,

Masatoshi Nomura,

Kensuke Egashira,

Beth Levine,

Junichi Sadoshima

Publication year - 2016

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.115.020502

Subject(s) - medicine , autophagy , pressure overload , heart failure , mitochondrion , cardiology , microbiology and biotechnology , apoptosis , biology , biochemistry , cardiac hypertrophy

Mitochondrial autophagy is an important mediator of mitochondrial quality control in cardiomyocytes. The occurrence of mitochondrial autophagy and its significance during cardiac hypertrophy are not well understood.

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