Open AccessResponse to Letters Regarding Article, “Clinical Management of Catecholaminergic Polymorphic Ventricular Tachycardia: The Role of Left Cardiac Sympathetic Denervation”
Author(s) -
Gaetano Maria De Ferrari,
Veronica Dusi,
Carla Spazzolini,
J. Martijn Bos,
Dominic J. Abrams,
Charles I. Berul,
Lia Crotti,
Michael Eldar,
М. С. Харлап,
Asaad Khoury,
Andrew D. Krahn,
Antoine Leenhardt,
Christopher R. Moir,
Attilio Odero,
Louise R.A. Olde Nordkamp,
Thomas Paul,
Ferran RosésNoguer,
М. A. Shkolnikova,
Jan Till,
Arthur A.M. Wilde,
Michael J. Ackerman,
Peter J. Schwartz
Publication year - 2016
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.115.019465
Subject(s) - catecholaminergic polymorphic ventricular tachycardia , medicine , sympathetic denervation , catecholaminergic , cardiology , denervation , tachycardia , catecholamine , ryanodine receptor 2 , ryanodine receptor , calcium
De Ferrari and colleagues1 have presented extremely important data on left cardiac sympathetic denervation in the management of patients with catecholaminergic polymorphic ventricular tachycardia. It is noteworthy that 24% of patients with complete denervation had clinical recurrences. This raises the question of whether these individuals are true nonresponders to complete denervation or whether a technically correct left cardiac sympathetic denervation, as described in the article, can be incomplete.Anatomic studies examining the cervicothoracic ganglion (CTG; stellate ganglion) and sympathetic trunk have shown considerable variability in the CTG. Importantly, the CTG does not exist as a fused structure …
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