Traffic-Related Air Pollution, Blood Pressure, and Adaptive Response of Mitochondrial Abundance
Author(s) -
Jia Zhong,
Akın Çayır,
Letizia Trevisi,
Marco Sánchez-Guerra,
Xinyi Lin,
Cheng Peng,
MarieAbèle Bind,
Diddier Prada,
Hannah E. Laue,
Kasey Brennan,
Alexandra E. Dereix,
David Sparrow,
Pantel Vokonas,
Joel Schwartz,
Andrea Baccarelli
Publication year - 2015
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.115.018802
Subject(s) - mitochondrial dna , blood pressure , medicine , quartile , confidence interval , diastole , cardiology , genetics , biology , gene
Exposure to black carbon (BC), a tracer of vehicular-traffic pollution, is associated with increased blood pressure (BP). Identifying biological factors that attenuate BC effects on BP can inform prevention. We evaluated the role of mitochondrial abundance, an adaptive mechanism compensating for cellular-redox imbalance, in the BC-BP relationship.
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