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Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects
Author(s) -
René Baudrand,
Luminita H. Pojoga,
Anand Vaidya,
Amanda Garza,
Paul A. Vöhringer,
Xavier Jeunemaı̂tre,
Paul N. Hopkins,
Tham M. Yao,
Jonathan S. Williams,
Gail K. Adler,
Gordon H. Williams
Publication year - 2015
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.115.016759
Subject(s) - aldosterone , medicine , endocrinology , statin , mineralocorticoid , blood pressure , angiotensin ii , corticosterone , diabetes mellitus , hormone
Statins substantially reduce cardiovascular mortality and appear to have beneficial effects independent of their lipid-lowering properties. We evaluated the hypothesis that statin use may modulate the secretion of aldosterone, a well-known contributor to cardiovascular disease.

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