Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation | Zendy

Arash Pezhouman | Zendy; Neha Singh | Zendy; Zhen Song | Zendy; Michael Nivala | Zendy; Anahita Eskandari | Zendy; Hong Cao | Zendy; Aneesh Bapat | Zendy; Christopher Y. Ko | Zendy; Thao P. Nguyen | Zendy; Zhilin Qu | Zendy; Hrayr S. Karagueuzian | Zendy; James N. Weiss | Zendy

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Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation

Author(s) -

Arash Pezhouman,

Neha Singh,

Zhen Song,

Michael Nivala,

Anahita Eskandari,

Hong Cao,

Aneesh Bapat,

Christopher Y. Ko,

Thao P. Nguyen,

Zhilin Qu,

Hrayr S. Karagueuzian,

James N. Weiss

Publication year - 2015

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.115.016217

Subject(s) - hypokalemia , dofetilide , medicine , afterdepolarization , ventricular tachycardia , ventricular fibrillation , cardiology , endocrinology , atrial fibrillation , repolarization , electrophysiology

Hypokalemia is known to promote ventricular arrhythmias, especially in combination with class III antiarrhythmic drugs like dofetilide. Here, we evaluated the underlying molecular mechanisms.

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