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Identifying Novel Biomarkers for Cardiovascular Events or Death in People With Dysglycemia
Author(s) -
Hertzel C. Gerstein,
Guillaume Paré,
Matthew McQueen,
Heinz Haenel,
Shun Fu Lee,
Janice Pogue,
Aldo P. Maggioni,
Salim Yusuf,
Sibylle Hess
Publication year - 2015
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.115.015744
Subject(s) - medicine , proportional hazards model , hazard ratio , myocardial infarction , biomarker , cause of death , stroke (engine) , clinical trial , confidence interval , disease , mechanical engineering , biochemistry , chemistry , engineering
Serum biomarkers may identify people at risk for cardiovascular (CV) outcomes. Biobanked serum samples from 8494 participants with dysglycemia in the completed Outcome Reduction With Initial Glargine Intervention trial were assayed for 284 biomarkers to identify those that could identify people at risk for a CV outcome or death when added to clinical measurements.

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