Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women | Zendy

Matti Marklund | Zendy; Karin Leander | Zendy; Max Vikström | Zendy; Federica Laguzzi | Zendy; Bruna Gigante | Zendy; Per Sjögren | Zendy; Tommy Cederholm | Zendy; Ulf dé Fairé | Zendy; Mai-Lis Hellénius | Zendy; Ulf Risérus | Zendy

Open Access

Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women

Author(s) -

Matti Marklund,

Karin Leander,

Max Vikström,

Federica Laguzzi,

Bruna Gigante,

Per Sjögren,

Tommy Cederholm,

Ulf dé Fairé,

Mai-Lis Hellénius,

Ulf Risérus

Publication year - 2015

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.115.015607

Subject(s) - eicosapentaenoic acid , medicine , hazard ratio , polyunsaturated fatty acid , linoleic acid , proportional hazards model , population , prospective cohort study , cohort study , cohort , lower risk , confidence interval , physiology , endocrinology , fatty acid , environmental health , biology , biochemistry

High intake of polyunsaturated fatty acids (PUFAs) may reduce the risk of cardiovascular disease (CVD) and mortality. Large, prospective studies including both sexes and circulating PUFAs as dietary biomarkers are needed. We investigated sex-specific associations of the major dietary PUFAs, eicosapentaenoic acid, docohexaenoic acid, linoleic acid, and α-linolenic acid, with incident CVD and all-cause mortality in a population-based cohort.

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