Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor | Zendy

Silvia Salem | Zendy; Vera Jankowski | Zendy; Yaw Asare | Zendy; Elisa A. Liehn | Zendy; Pia Welker | Zendy; Ana I. Raya | Zendy; Carmen Pineda | Zendy; Mariano Rodríguez | Zendy; Juan R. MuñozCastañeda | Zendy; Heike Bruck | Zendy; Nikolaus Marx | Zendy; Fernanda Brandão Machado | Zendy; Mareike Staudt | Zendy; Georg Heinze | Zendy; Walter Zidek | Zendy; Joachim Jankowski | Zendy

Open Access

Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor

Author(s) -

Silvia Salem,

Vera Jankowski,

Yaw Asare,

Elisa A. Liehn,

Pia Welker,

Ana I. Raya,

Carmen Pineda,

Mariano Rodríguez,

Juan R. MuñozCastañeda,

Heike Bruck,

Nikolaus Marx,

Fernanda Brandão Machado,

Mareike Staudt,

Georg Heinze,

Walter Zidek,

Joachim Jankowski

Publication year - 2015

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.114.013168

Subject(s) - angiotensin ii , endocrinology , medicine , renin–angiotensin system , vasoconstriction , receptor , angiotensin receptor , angiotensin ii receptor type 1 , vasodilation , biology , blood pressure

The renin-angiotensin system and especially the angiotensin peptides play a central role in blood pressure regulation. Here, we hypothesize that an as-yet unknown peptide is involved in the action of angiotensin II modulating the vasoregulatory effects as a cofactor.

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