Open AccessResponse to Letter Regarding Article, “Warfarin Use and the Risk for Stroke and Bleeding in Patients With Atrial Fibrillation Undergoing Dialysis”
Author(s) -
Mitesh Shah,
Meytal Avgil Tsadok,
Cynthia A. Jackevicius,
Vidal Essebag,
Mark J. Eisenberg,
Elham Rahme,
Karin H. Humphries,
Jack V. Tu,
Hassan Behlouli,
Helen Guo,
Louise Pilote
Publication year - 2014
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.114.012785
Subject(s) - medicine , atrial fibrillation , warfarin , stroke (engine) , dialysis , stroke risk , major bleeding , cardiology , intensive care medicine , ischemic stroke , mechanical engineering , engineering , ischemia
Qureshi and colleagues mentioned that they observed a 72% increase in the risk of gastrointestinal bleeding in hemodialysis patients with atrial fibrillation (AF) who were on warfarin compared with those not on warfarin and questioned the only 44% increase in the risk of bleeding in dialysis patients with AF who were on warfarin compared with those not on warfarin in our study.1,2 Contrary to only gastrointestinal bleeding in the study by Khalid et al,1 the “bleeding” definition in our study included intracerebral bleeding, gastrointestinal bleeding, intraocular bleeding, hematuria, and unspecified location of bleeding, which could be a possible reason for the difference in bleeding risk between the 2 studies.1,2 Similar to Khalid et al,1 Winkelmayer and colleagues3 studied the association …
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