Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation | Zendy

Lars Wallentin | Zendy; Ziad Hijazi | Zendy; Ulrika Andersson | Zendy; John H. Alexander | Zendy; Raffaele De Caterina | Zendy; Michael Hanna | Zendy; John D. Horowitz | Zendy; Elaine M. Hylek | Zendy; Renato D. Lópes | Zendy; Signild Åsberg | Zendy; Christopher B. Granger | Zendy; Agneta Siegbahn | Zendy

Open Access

Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation

Author(s) -

Lars Wallentin,

Ziad Hijazi,

Ulrika Andersson,

John H. Alexander,

Raffaele De Caterina,

Michael Hanna,

John D. Horowitz,

Elaine M. Hylek,

Renato D. Lópes,

Signild Åsberg,

Christopher B. Granger,

Agneta Siegbahn

Publication year - 2014

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.114.011204

Subject(s) - medicine , atrial fibrillation , oxidative stress , inflammation , risk factor , cardiology , c reactive protein

Growth differentiation factor 15 (GDF-15), high-sensitivity troponin, and N-terminal pro-brain natriuretic peptide levels are predictive of death and cardiovascular events in healthy elderly subjects, patients with acute coronary syndrome, and patients with heart failure. High-sensitivity troponin I and N-terminal pro-brain natriuretic peptide are also prognostic in patients with atrial fibrillation. We evaluated the prognostic value of GDF-15 alone and in addition to clinical characteristics and other biomarkers in patients with atrial fibrillation.

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