Paradoxical Normoxia-Dependent Selective Actions of Inorganic Nitrite in Human Muscular Conduit Arteries and Related Selective Actions on Central Blood Pressures | Zendy

Sami A. Omar | Zendy; Henry Fok | Zendy; Katharina Tilgner | Zendy; Ashok Nair | Zendy; Joanne Hunt | Zendy; Benyu Jiang | Zendy; Paul Taylor | Zendy; Phil Chowienczyk | Zendy; David J. Webb | Zendy

Open Access

Paradoxical Normoxia-Dependent Selective Actions of Inorganic Nitrite in Human Muscular Conduit Arteries and Related Selective Actions on Central Blood Pressures

Author(s) -

Sami A. Omar,

Henry Fok,

Katharina Tilgner,

Ashok Nair,

Joanne Hunt,

Benyu Jiang,

Paul Taylor,

Phil Chowienczyk,

David J. Webb

Publication year - 2014

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.114.009554

Subject(s) - medicine , vascular resistance , vasodilation , nitrite , sodium nitrite , artery , nitric oxide , anesthesia , cardiology , blood pressure , hemodynamics , chemistry , organic chemistry , nitrate

Inorganic nitrite dilates small resistance arterioles via hypoxia-facilitated reduction to vasodilating nitric oxide. The effects of nitrite in human conduit arteries have not been investigated. In contrast to nitrite, organic nitrates are established selective dilators of conduit arteries.

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