Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study
Author(s) -
Marguerite R. Irvin,
Degui Zhi,
Roby Joehanes,
Michael Mendelson,
Stella Aslibekyan,
Steven A. Claas,
Krista S. Thibeault,
Nikita Patel,
Kenneth Day,
Lindsay Waite Jones,
Liming Liang,
Brian H. Chen,
Chen Yao,
Hemant K. Tiwari,
José M. Ordovás,
Daniel Levy,
Devin Absher,
Donna K. Arnett
Publication year - 2014
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.114.009158
Subject(s) - epigenome , medicine , blood lipids , genome wide association study , physiology , genetic association , genetics , bioinformatics , cholesterol , single nucleotide polymorphism , gene , dna methylation , genotype , biology , gene expression
Genetic research regarding blood lipids has largely focused on DNA sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of DNA methylation may uncover epigenetic factors influencing lipid metabolism.
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