Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue | Zendy

Xiaofeng Li | Zendy; Mengyu Zhu | Zendy; Mark E.T. Penfold | Zendy; Rory R. Koenen | Zendy; Anna Thiemann | Zendy; Kathrin Heyll | Zendy; Shamima Akhtar | Zendy; Seena Koyadan | Zendy; Zhuojun Wu | Zendy; Felix Gremse | Zendy; Fabian Kießling | Zendy; Marc van Zandvoort | Zendy; Thomas J. Schall | Zendy; Christian Weber | Zendy; Andreas Schober | Zendy

Open Access

Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue

Author(s) -

Xiaofeng Li,

Mengyu Zhu,

Mark E.T. Penfold,

Rory R. Koenen,

Anna Thiemann,

Kathrin Heyll,

Shamima Akhtar,

Seena Koyadan,

Zhuojun Wu,

Felix Gremse,

Fabian Kießling,

Marc van Zandvoort,

Thomas J. Schall,

Christian Weber,

Andreas Schober

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.006840

Subject(s) - medicine , hyperlipidemia , adipose tissue , cholesterol , endocrinology , diabetes mellitus

The aim of this study was to determine the role of the chemokine receptor CXCR7 in atherosclerosis and vascular remodeling. CXCR7 is the alternative receptor of CXCL12, which regulates stem cell-mediated vascular repair and limits atherosclerosis via its receptor, CXCR4.

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