Assessment of Atherosclerosis in Chronic Granulomatous Disease | Zendy

Christopher T. Sibley | Zendy; Tyra Estwick | Zendy; Anna Zavodni | Zendy; ChiungYu Huang | Zendy; Alan C. Kwan | Zendy; Benjamin P. Soule | Zendy; Debra A. Long Priel | Zendy; Alan T. Remaley | Zendy; Amanda K. Rudman Spergel | Zendy; Evrim Türkbey | Zendy; Douglas B. Kuhns | Zendy; Steven M. Holland | Zendy; Harry L. Malech | Zendy; Kol A. Zarember | Zendy; David A. Bluemke | Zendy; John I. Gallin | Zendy

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Assessment of Atherosclerosis in Chronic Granulomatous Disease

Author(s) -

Christopher T. Sibley,

Tyra Estwick,

Anna Zavodni,

ChiungYu Huang,

Alan C. Kwan,

Benjamin P. Soule,

Debra A. Long Priel,

Alan T. Remaley,

Amanda K. Rudman Spergel,

Evrim Türkbey,

Douglas B. Kuhns,

Steven M. Holland,

Harry L. Malech,

Kol A. Zarember,

David A. Bluemke,

John I. Gallin

Publication year - 2014

Publication title -

circulation

Language(s) - English

Resource type - Journals

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.006824

Subject(s) - medicine , chronic granulomatous disease , cardiology , magnetic resonance imaging , c reactive protein , nadph oxidase , case control study , coronary artery disease , subclinical infection , inflammation , gastroenterology , pathology , immunology , radiology , oxidative stress

Patients with chronic granulomatous disease (CGD) experience immunodeficiency because of defects in the phagocyte NADPH oxidase and the concomitant reduction in reactive oxygen intermediates. This may result in a reduction in atherosclerotic injury.

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